vit_r

Мышинно-требовательная возня

RE is a socio-technical discipline that aims to understand and analyze the needs of stakeholders affected by the introduction of digital solutions and to communicate these needs to the development team. This mediator role enables our community to have a major impact on the goals, capabilities, functionalities and qualities of digital solutions and thus take RESPONSIBILITY for the social impact that these solutions bring.

With this special theme we aim to raise awareness for this “Social REsponsibility”, to share challenges / ideas / project experience and to foster discussions around the following questions:

• How can our RE community contribute to the “social good”?


• How to support “Responsible Design” through requirements engineering?


• How to actively involve the society (respectively large / heterogeneous stakeholder groups) into RE activities (e.g., co-creation / co-design)?


• How to systematically derive, engineer and evaluate social values and impact?


• How to align social needs and “intelligent” systems evolution?

The Agile Work Creeping

         ...
    Data Reading                    (1.  / Software)
          |              
          |              
          V              
     Confirmation                   (2.  / Software)
    Dialog Window
     Preparation     
          |          
          |          
          V          
       Manual                       (3.  / User)  
   Data Confirmation      
          |
          |            
          V            
       Further                      (4.  / Software)    
   Data Processing
         ...

The State Transition Table of the Agile Age

private static final int[][] STATE_TRANSITION_TABLE  = {
    //================================================================================================|
    //                   || INIT          | CHECK_PRECOND | REGISTRATION  | WAIT_ACCEPTED | LEVEL_OK  |
    //================================================================================================|
    /*  START        */   { CHECK_PRECOND , _ignore       , INT_ERROR     , INT_ERROR     , INT_ERROR }
    //-------------------++---------------+---------------+---------------+---------------+-----------|
    /*  PRECOND_OK   */  ,{ INIT          , REGISTRATION  , INT_ERROR     , WAIT_ACCEPTED , INT_ERROR }
    //-------------------++---------------+---------------+---------------+---------------+-----------|
    /*  PRECOND_FAIL */  ,{ INIT          , INIT          , INT_ERROR     , INT_ERROR     , INT_ERROR }
    //-------------------++---------------+---------------+---------------+---------------+-----------|
    /*  REG_DONE     */  ,{ _ignore       , CHECK_PRECOND , WAIT_ACCEPTED , INT_ERROR     , INT_ERROR }
    //-------------------++---------------+---------------+---------------+---------------+-----------|
    /*  REG_FAIL     */  ,{ _ignore       , INT_ERROR     , INIT          , INT_ERROR     , INT_ERROR }
    //-------------------++---------------+---------------+---------------+---------------+-----------|
    /*  ACCEPTED     */  ,{ INT_ERROR     , INT_ERROR     , INT_ERROR     , LEVEL_OK      , _ignore   }
    //-------------------++---------------+---------------+---------------+---------------+-----------|
    };

Посты LJ
Тип: "Suspended Entry"
Время закрытия цензурой:
до семи суток с момента опубликования
Январь 2023

У Вас ещё есть десять секунд, чтобы отказаться.

Внимание!
Начался обратный отсчёт!

Рабочие материалы. Русская игра с китайскими шарами

Although there is the possibility of a greater risk of morbidity and mortality in infected populations that are also at risk for impaired nutrition, we emphasize that the degree of Se deficiency seen in this study is more pronounced than that generally seen in human populations, except perhaps in the areas of China where Keshan disease is found. Infecting mice with influenza virus induces an interstitial pneumonitis that is characterized by an influx of T and B cells and macrophages to the infected lung. The mouse has long been used to study influenza virus infection and pathogenesis.

Our data demonstrated that, as with Se‐deficient coxsackievirus‐infected mice, Se‐deficient mice infected with Influenza A/Bangkok/1/79 exhibited increased pathology when compared with infected Se‐adequate mice. Se‐adequate mice infected with Influenza A/Bangkok/1/79 develop a relatively mild inflammatory response. However, the inflammation is much more severe in the Se‐deprived animals.
...
In summary, mice fed a diet deficient in Se develop much more severe lung pathology post‐ influenza virus infection than Se‐adequate mice. Although the increase in lung pathology was not associated with an increase in viral titer, it was associated with an increase in the mRNA expression of pro‐inflammatory cytokines and chemokines and a decrease in the expression of anti‐inflammatory cytokines. Furthermore, the immune response in the infected lung tissue was shifted away from a TH1 response and toward a TH2 response in the Se‐deficient mice. Our work points to the importance of adequate antioxidant defense mechanisms for protection against viral infection and demonstrates that Se‐dependent GSH‐Px may play an important role during an influenza‐induced inflammatory process.

golos-dobra

Нет, мы вошли в область Галактического Хаоса.
И Ужаса заодно, но это второстепенно.